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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TERF1 All Species: 1.21
Human Site: S434 Identified Species: 2.96
UniProt: P54274 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P54274 NP_003209.2 439 50246 S434 M K K L K L I S S D S E D _ _
Chimpanzee Pan troglodytes XP_001164723 439 50325 C434 M K K L K L I C S D S E D _ _
Rhesus Macaque Macaca mulatta XP_001083645 438 50257 C433 M K K L K L I C S D S E D _ _
Dog Lupus familis XP_546856 470 51528 S454 P K Y E D L C S S F G A G W W
Cat Felis silvestris
Mouse Mus musculus P70371 421 48205 R416 D R W R T M K R L K L I S _ _
Rat Rattus norvegicus NP_001012482 421 47744 R416 D R W R T M R R L R L I S _ _
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001516615 412 47652 D405 L K K L D L V D L E S E P T N
Chicken Gallus gallus NP_989711 354 40991
Frog Xenopus laevis NP_001084426 420 49257 D415 M K R L K I V D S D C D L _ _
Zebra Danio Brachydanio rerio XP_695329 367 42492 K362 D R W R V L K K Q N L V S _ _
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.4 96.5 21.9 N.A. 64.2 65.3 N.A. 20.9 38.7 40.3 29.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 98.8 97.7 40.4 N.A. 75.6 75.6 N.A. 40 53.5 58.7 48.9 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 92.3 92.3 26.6 N.A. 0 0 N.A. 40 0 46.1 7.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 92.3 92.3 26.6 N.A. 15.3 15.3 N.A. 60 0 76.9 23 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 0 % A
% Cys: 0 0 0 0 0 0 10 20 0 0 10 0 0 0 0 % C
% Asp: 30 0 0 0 20 0 0 20 0 40 0 10 30 0 0 % D
% Glu: 0 0 0 10 0 0 0 0 0 10 0 40 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 10 0 10 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 10 30 0 0 0 0 20 0 0 0 % I
% Lys: 0 60 40 0 40 0 20 10 0 10 0 0 0 0 0 % K
% Leu: 10 0 0 50 0 60 0 0 30 0 30 0 10 0 0 % L
% Met: 40 0 0 0 0 20 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 10 % N
% Pro: 10 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Q
% Arg: 0 30 10 30 0 0 10 20 0 10 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 0 20 50 0 40 0 30 0 0 % S
% Thr: 0 0 0 0 20 0 0 0 0 0 0 0 0 10 0 % T
% Val: 0 0 0 0 10 0 20 0 0 0 0 10 0 0 0 % V
% Trp: 0 0 30 0 0 0 0 0 0 0 0 0 0 10 10 % W
% Tyr: 0 0 10 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 70 70 % _